Researchers test DNA editing, recommend steps to improve accuracy

genetic results

  • Screening clones for mutations and large copy number alterations acquired in culture to determine the largest source of genomic divergence between clonal lines.
  • Excluding from consideration clones with large copy number alterations or mutations having potentially functional consequences.
  • Comparing a mix of multiple unedited clones with that of edited clones to dilute the possible effect of mutations in each clone.

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