Researchers pinpoint neurochemical marker linked with loss of motor function in ALS

$Overview of the processing pipeline. Spectral signatures of neurometabolites of interest were obtained from the primary motor cortex (PMC) (magnetic resonance spectroscopy (MRS)) voxel. The MRS voxel underwent segmentation into gray matter (GM) and white matter (WM) tissue classes, which respectively underwent analyses of functional connectivity and diffusion tensor imaging. FA, fractional anisotropy; rsFC, resting-state functional connectivity. Credit: Journal of Neurology, Neurosurgery & Psychiatry (2022). DOI: 10.1136/jnnp-2022-329993$

Identifying the marker

A step toward a definitive test

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