The Polycystic ovary syndrome (PCOS) is the most common hormonal disorder in women of childbearing age. It leads to an irregular cycle and increases the risk of Diabetes by the 2 – to 9-fold. In addition to the conventional treatment of the symptoms with a hormone pill on the anti-diabetic drug Metformin is considered to be a possible treatment option.
One of the eight young women affected by PCOS. They often have increased body hair, tend to cycle disturbances and Obesity. "Another significant characteristic of PCOS, the underlying insulin resistance. This reduces the sensitivity of the body cells to respond to Insulin and regulate the glucose metabolism optimally," lecturer Dr. med declared Private. Susanne Lively Tan, senior physician of the clinic for endocrinology and metabolic diseases at the University hospital in Essen, at the Congress of the German Diabetes society in Berlin. "This leads to an Excess of Insulin in the blood, which in turn promotes weight gain and the formation of male hormones." Approximately every tenth woman with PCOS get type 2 Diabetes.
In order to regulate the cycle and the hair growth, many women the Anti-Baby-pill. As soon as women with the desire to have children stop taking the pill, you experience the symptoms again. An Alternative form of treatment is the administration of Metformin. The Diabetes drug, improves insulin resistance, but may also reduce the male hormones to measure. As a result, the hair goes back, the cycle is regulated, and the pregnancy rate is increased. In addition, Metformin helps to reduce the weight and lowers the risk for the development of Diabetes.
Metformin is not approved for the treatment of PCOS yet, but after medical consultation as a so-called "off-label Therapie" be used. The funds to reimburse the costs of treatment only if there is already a Diabetes is present. In General, the following applies: "In the case of PCOS, it is advisable to examine women on a possible Diabetes or pre-stages of Diabetes," so Reger-Tan. "Depending on the risk profile of such a Screening should be repeated every two to three years."
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